| 1899 |
Ennosuke Amano started pharmaceutical business. |
| 1939 |
Genichi Amano started pharmaceutical business in China. |
| 1948 |
Amano Pharmaceutical Co., Ltd. incorporated in Nagoya, Japan.
Started production of digestive enzyme, Malt Diastase. |
| 1950 |
Established Nishiharu Enzyme Plant with fungal amylase production. |
| 1960 |
Established an Enzyme Research And Development Center. |
| 1961 |
Started production of food-processing enzyme, Glucoamylase. |
| 1969 |
Established Nagoya Enzyme Plant. |
| 1970 |
Started production of diagnostic enzyme, Lipoprotein Lipase. |
| 1976 |
Established Yoro Enzyme Plant. |
| 1980 |
Pancreatin production technology was transferred to China. |
| 1981 |
Established Amano International Enzyme Co., Ltd. in USA. |
| 1983 |
Opened a Liaison Office in Frankfurt, Germany. |
| 1988 |
Established Amano Enzyme USA Co., Ltd. in Virginia, USA. |
| 1992 |
Established Amano Enzyme Europe Ltd. in U.K.. |
| 1993 |
New corporate strategy "World No.1 Speciality Enzyme Producer" |
| 1995 |
Nagoya Enzyme Plant registered ISO 9002. |
| 2000 |
Amano Enzyme Inc. (New corporate name)
Opened Gifu R&D Center in Gifu, Japan.
All divisions registered ISO 9001. |
| 2001 |
Acquired majority shares of Daiwa Kasei K.K..
All divisions registered ISO 14001. |
| 2003 |
Opened a Liaison Office in Shanghai. |
| 2004 |
All three plants were Kosher certified by Orthodox Union. |
| 2006 |
Acquired all shares of IGM.
(New corporate name, Amano Enzyme de Mexico s.a. de c.v. ) |
| 2007 |
Established Amano Enzyme China Ltd. in Shanghai. |
| 2009 |
Established Amano Enzyme Manufacturing (China) Ltd. |
